Department of Bioengineering
Bioengineering research and education at UC Berkeley
Updated: 1 hour 46 min ago
mFluiDx, a startup founded by BioE PhD alum Charlie Yeh and currently in the CITRIS Foundry incubator, has published their development of a portable, self-powered, low-cost nucleic acid detection chip. This simple chip allows rapid quantitative digital nucleic acid detection directly from small human blood samples, an alternative to real-time PCR testing in remote or low-resource settings.
Herr Lab advances protein expression profiling of circulating tumor cells using microfluidic western blotting
Circulating tumor cells (CTCs) are detached primary cancer cells found in the circulatory system that are implicated in the metastasis of cancer. Herr and collaborators have developed a microfluidic western blot for an 8-plex protein panel for individual CTCs, derived from estrogen receptor positive breast cancer patients, that advances the state of the art in CTC characterization with tiny sample sizes.
See how students in bioengineering and other fields are working at the intersection of design and health at the Jacobs Institute for Design Innovation.
A capstone team of bioengineering MEng students is developing nanocarriers to deliver medicine to inaccessible regions of the brain to treat neurologic and brain-related diseases.
BioE startups GenEdit (Prof Niren Murthy and PhD Kunwoo Lee) and SmartPhage (MEng Job Shiach) have completed their time as members of the CITRIS Foundry's startup program and are going out to change the world.
Alumni company Bolt Threads has launched its first direct to consumers clothing made of synthetic spider silk - a snazzy tie! Only 50 will be made, but more engineered clothing is on the horizon.
A recent proof-of-concept study shows that a tiny portable microjet injector called MucoJet can deliver a high-pressure stream of liquid and immune system-triggering molecules that penetrate the mucosal layer of the mouth to stimulate an immune response in the buccal region. The jet is pressurized, but not uncomfortably so, and would remove the sting of needles. Postdoctoral scholar Kiana Aran is lead investigator on the study.
UC Berkeley is a partner in one of two newly established Resource Centers as part of the The National Institute of Dental and Craniofacial Research’s Dental, Oral, and Craniofacial Tissue Regeneration Consortium (DOCTRC). Aimed at developing resources and strategies for regenerating dental, oral, and craniofacial tissues that have been damaged by disease or injury, the Center for Dental, Oral, and Craniofacial Tissue and Organ Regeneration (C-DOCTOR) is a partnership between UC Berkeley, UCSF, USC, UC Davis, UCLA, and Stanford. Professor Kevin Healy is the principal investigator at Berkeley.
Professor Michael Yartsev was named a 2017 Sloan Research Fellow. The Alfred P. Sloan Foundation selected 126 outstanding U.S. and Canadian researchers as the recipients of the 2017 fellowships, honoring early-career scholars whose achievements mark them as the next generation of scientific leaders.
New research from Professor Sanjay Kumar's lab uncovers fundamental design principles of how cells and tissues define and maintain their structure, combining sophisticated micropatterning technologies to engineer cell shape, laser nanosurgery to cut individual stress fibers with light and probe their internal structure, and mathematical modeling. Cell shape is critical in development, wound healing, stem cell differentiation, and cancer, among other processes. The lead author is bioengineering PhD student Elena Kassianidou .
Professor Adam Arkin will lead the new NASA Center for the Utilization of Biological Engineering in Space (CUBES), a Space Technology Research Institute to advance research into an integrated, multi-function, multi-organism bio-manufacturing system to produce fuel, materials, pharmaceuticals and food on long-term space missions.
The Chan Zuckerberg Biohub has announced it's inaugural class of 47 faculty investigators from UC Berkeley, UCSF and Stanford, including three Berkeley Bioengineers. Professors Dan Fletcher, Amy Herr and Aaron Streets are among the 13 Berkeley faculty who will receive up to $1.5 million each over the next five years to conduct cutting-edge biomedical research.
Professor Steven Conolly’s lab has won the 2017 Excellence in Laboratory Safety Award in the Large Physical Sciences Lab category. Winners were selected based on consideration of the lab’s safety inspection results, internal safety communications, and collaboration with EH&S and Department Safety Coordinators.
Lawrence Berkeley National Lab began construction of the Integrative Genomics Building (IGB), which will house researchers from the Department of Energy Joint Genome Institute with those from the Systems Biology Knowledgebase under one roof. Bioengineering professors Adam Arkin, Director of Kbase, and Jay Keasling, Biosciences Associate Laboratory Director, were on hand for the groundbreaking.
Research from Professor Mohammad Mofrad's lab, "Bacterial Networks on Hydrophobic Micropillars", made the cover of the journal ACS Nano this issue.
Healy Lab's heart-on-a-chip technology is the subject of a video feature at Futurism.
Professor Amy Herr has been named the the inaugural faculty director of the Bakar Fellows Program at UC Berkeley. The program fosters faculty entrepreneurship in the STEM+ fields including Engineering, Computer Science, Chemistry, Biological Sciences, Physical Sciences, and Architecture, to help professors translate their ground-breaking discoveries into practical solutions and contribute to Berkeley's entrepreneurial ecosystem. Herr was a member of the first class of Bakar Fellows in 2012.
Bioengineering MEng students Sneha Balan and Nick Engel are featured on page 4 of the Winter MEng newsletter, for their Early Cancer Detection project and Alumni Innovation Award. Nick is also on the cover.
After severe trauma, some patients in shock develop impaired coagulation. This is difficult to diagnose in crisis and makes blood transfusions dangerously challenging to manage. Professor Adam Arkin and collaborators have used dynamic modeling to demonstrate a method for calculating each patient’s transfusion requirements using only laboratory values that can be easily and quickly obtained in the emergency setting. This personalized information could help hospitals save lives at risk from acute traumatic coagulopathy and massive transfusion mortality.
Congratulations 2013 PhD Tim Downing, now a professor at UC Irvine, named to the 2017 Forbes 30 Under 30 for his work examining how extracellular signals can influence the final fate of cells.