Researchers in Professor Niren Murthy’s lab have developed a way to efficiently deliver therapeutic transcription factors in living cells. Transcription factors are proteins that initiate and regulate the transcription of genes – a promising method for new treatments, but with significant delivery problems.
First author Kunwoo Lee, a PhD candidate in the UC Berkeley – UCSF Graduate Program in Bioengineering, has developed DARTs (DNA assembled recombinant transcription factors), a multifunctional oligonucleotide (short DNA or RNA molecule) with a unique molecular architecture. This allows them to bind transcription factors, trigger absorption by liver cells, and stimulate escape from the cell’s transportation structure.
Their research was published today in Nature Materials.
BioE senior capstone design team of Hannah Adelsberg, Celia Cheung, Eric Katz, and Suzanne Chou took second place at the annual Stanford Design Challenge for their invention, the HandleBar. HandleBar is a ratcheting stair assist railing for older people to safely ascend and descend stairs in their homes, allowing for increased independence while still encouraging individuals to climb under their own power.
The Stanford Center on Longevity Design Challenge is a global competition aimed at encouraging students to design products and services to improve the lives of older adults. In this second year, the Challenge focused on ways to motivate / empower mobility among older adults in their daily lives, both inside their homes and in their community.
On April 4, over 100 students, parents, and teachers from throughout the Bay Area gathered at Stanley Hall for the second annual Bioengineering High School Competition (BioEHSC).
BioEHSC, which is run by the Bioengineering Honor Society, is a 6-week bioengineering design competition aimed at high school students. This culminates in a final symposium where students share their proposals to solve pervasive medical issues using bioengineering strategies.
Research by Professor Robert Dudley and postdoc Victor Ortega is featured in a segment on KQED Science about Hummingbirds in a wind tunnel.
Lindsey Dougherty’s love of the sea eventually led her to UC Berkeley, where she is now a graduate student focusing on one of the ocean’s more unusual critters: a clam that flashes in the deep.
This behavior earned it the nickname ‘disco clam,’ and Dougherty is working with UC Berkeley’s Roy Caldwell, professor of integrative biology, to explore how and why it flashes its mirrored lips.